Tricuspid Regurgitation

Normal path
of blood flow


What is Tricuspid Regurgitation?

Tricuspid regurgitation (TR) is a disorder in which the heart’s tricuspid valve does not close properly, causing blood to flow backward (leak) into the right upper heart chamber (atrium) when the right lower heart chamber (ventricle) contracts, reducing its efficiency1. Severe TR affects more than 1.6 million patients in the U.S. today2.

The onset of tricuspid regurgitation may be due to a structural change of components of the tricuspid valve apparatus, a lesion can be primary (intrinsic abnormality) or secondary/functional (right ventricular dilatation)1.

What are Symptoms of Tricuspid Regurgitation?

Tricuspid regurgitation may not cause any symptoms if the regurgitation is not severe. However, patients may experience1:

  • Active pulsing in the neck veins
  • Decreased urine output
  • Fatigue, tiredness
  • General swelling
  • Swelling of the abdomen
  • Swelling of the feet and ankles
  • Weakness

2 Stuge O, Liddicoat J. Emerging opportunities for cardiac surgeons within structural heart disease. J Thorac Cardiovasc Surg 2006;132:1258–61.